5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 881677-11-8 |
| Product name | 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 881677-11-8
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 881677-11-8 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 881677-11-8
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing anticancer agents or kinase inhibitors | Multistep organic synthesis involving sulfonation, condensation, and functional group transformations |
| Medicinal Chemistry | Building block for constructing bioactive molecule libraries containing pyrrole and pyridine sulfonyl motifs | Compound design and synthesis prior to high-throughput screening |
| Organic Synthesis | Molecular building block for constructing complex heterocyclic systems | Derivatization reactions based on the aldehyde group, including Wittig, reductive amination, and Knoevenagel reactions |
Manufacturing Quality Control of 881677-11-8
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, condition, and presence of visible foreign substances under natural light or standard light source. |
| Identification (Identity) | High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | HPLC: Preliminary identification by comparing retention time with reference standards; NMR: Analyze ¹H and ¹³C spectra to confirm structural features; MS: Measure molecular ion peak (e.g., ESI-MS) to verify molecular weight. |
| Purity/Content | High-Performance Liquid Chromatography (HPLC) | Use reverse-phase HPLC (e.g., C18 column), UV detector (based on compound's maximum absorption wavelength ~254–310 nm), calculate purity or content using external standard method or area normalization method. |
| Impurity Analysis | HPLC-DAD or LC-MS | Detect related substances (organic impurities), including starting materials, intermediates, degradation products, etc.; identify by comparison with impurity reference standards or speculate structure via LC-MS. |
| Residual Solvents | Gas Chromatography (GC) | Detect solvents potentially remaining from the manufacturing process (e.g., methanol, ethanol, dichloromethane, DMF), using headspace GC-FID; comply with ICH Q3C guidelines. |
| Moisture | Karl Fischer Titration | Determine moisture content in the sample, suitable for quality control of active pharmaceutical ingredients to ensure stability. |
| Melting Point | Melting Point Apparatus Method | Measure the melting range of the compound using automatic or capillary melting point apparatus as a physical property reference. |
| C polymorph (if applicable) | X-ray Powder Diffraction (XRPD) | If multiple polymorphic forms exist, used for identification and control of the preferred polymorph to ensure batch consistency. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectrometry (AAS) | Detect heavy metal impurities such as lead, cadmium, mercury, arsenic, etc., in compliance with ICH Q3D elemental impurity limits. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | Carbonize the sample, add sulfuric acid, and incinerate until constant weight to determine total inorganic impurities; suitable for solid APIs. |
Technical Specifications of 881677-11-8
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 881677-11-8
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 881677-11-8
Packaging of 881677-11-8
Industrial 881677-11-8 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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