China Factory Direct
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| CAS number | 881891-82-3 |
| Product name | 2-CHLORO-3-FLUORO-4-METHYLPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel fluorinated pyridine-based insecticides and fungicides | Used to construct active molecular scaffolds via nucleophilic substitution, coupling reactions, or catalyzed cross-coupling reactions with amines, phenols, or heterocyclic compounds |
| Pharmaceuticals | Fluorinated heterocyclic building block for antiviral, antitumor, or central nervous system drugs | Applied as a key intermediate in Suzuki coupling, Buchwald-Hartwig amination, or N-alkylation to construct core drug structures |
| Dyes & Functional Materials | Precursor for fluorinated optoelectronic materials or fluorescent probes | Used to incorporate fluoropyridine units via Friedel-Crafts alkylation, metal-catalyzed coupling, or intramolecular cyclization to modulate electronic transport properties of materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies main component by retention time and peak area comparison against certified reference standard. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Identifies and semi-quantifies impurities based on retention time and mass spectral fragmentation patterns. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile organic solvents by equilibrium partitioning into headspace followed by GC separation. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines water via electrochemical iodine generation and stoichiometric reaction with water. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using ion-exchange column and conductivity detection. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Detects trace metal elements (e.g., Pb, Cd, Hg, As) by atomic emission after plasma atomization. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralizes acidic impurities using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against specified criteria in controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral centers in solution at specified concentration and path length. |
| Bulk Density | ASTM D1895 Method A | Determines mass per unit volume of freely settled powder using standardized graduated cylinder and balance. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/25°C) | 1.22–1.24 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.