2-Chloro-5-fluoro-4-methyl-pyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 881891-83-4 |
| Product name | 2-Chloro-5-fluoro-4-methyl-pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-5-fluoro-4-methyl-pyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-5-fluoro-4-methyl-pyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-5-fluoro-4-methyl-pyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for novel insecticides and acaricides, used in the synthesis of neonicotinoid insecticides such as flupyradifurone | Undergoes nucleophilic substitution with amines to construct C–N bonds |
| Pharmaceuticals | Structural motif for fluorinated heterocyclic drugs, employed in synthesizing anticancer and antiviral drug candidates | Participates in transition metal-catalyzed cross-coupling reactions, including Suzuki and Heck couplings |
| Materials Science | Functional building block for organic light-emitting diodes (OLEDs) and electron-transport materials | Introduces fluoropyridyl groups via halogen exchange or direct arylation to tune HOMO/LUMO energy levels |
Manufacturing Quality Control of 2-Chloro-5-fluoro-4-methyl-pyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or HPLC-UV | Quantitative determination using calibrated chromatographic separation and detection of the main peak area relative to a reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally similar impurities using reversed-phase chromatography with UV detection. |
| Residual Solvents | GC-FID with headspace sampling | Volatile organic solvents are extracted into headspace gas and quantified by flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration based on the reaction of iodine with water in a methanol-based reagent. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals | ICP-OES | Multi-element detection of metallic impurities after acid digestion, based on atomic emission spectroscopy. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile inorganic residue measured after high-temperature incineration of the sample. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition temperature determined by observing solid-to-liquid phase change under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established visual standards under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen ion activity determined using calibrated glass electrode and reference electrode system. |
| Bulk Density | Tap Density Analyzer | Mass per unit volume measured after standardized mechanical tapping of a powder sample in a graduated cylinder. |
Technical Specifications of 2-Chloro-5-fluoro-4-methyl-pyridine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-5-fluoro-4-methyl-pyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-5-fluoro-4-methyl-pyridine
Safety Information of 2-Chloro-5-fluoro-4-methyl-pyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Chloro-5-fluoro-4-methyl-pyridine
Industrial 2-Chloro-5-fluoro-4-methyl-pyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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