China Factory Direct
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| CAS number | 88224-05-9 |
| Product name | L-Isoleucine allyl ester p-toluenesulfonate salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediate | Used in the synthesis of peptide-based and chiral pharmaceuticals as a protected derivative of L-isoleucine for coupling reactions |
| Organic synthesis | Amino acid ester protecting reagent | Applied as an α-amino-protected amino acid ester in peptide bond formation, compatible with both solid-phase and liquid-phase peptide synthesis processes |
| Fine chemicals | Synthetic building block | Employed in asymmetric synthesis and catalytic transformations to construct complex organic molecular frameworks |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (L-Isoleucine Allyl Ester p-Toluenesulfonate) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content determined by relative peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based reagent. |
| Residual Solvents (e.g., methanol, ethyl acetate) | Gas Chromatography (GC) with FID | Separation and quantification of volatile organic solvents using capillary column and flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Sulfonate Counterion (p-toluenesulfonic acid content) | Ion Chromatography (IC) | Anion separation and quantification using suppressed conductivity detection. |
| Related Substances | HPLC with UV detection | Detection and quantification of structurally related impurities (e.g., free L-isoleucine, allyl alcohol, toluene sulfonic acid) using gradient elution. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light source in solution at controlled temperature and concentration. |
| Residue on Ignition | Gravimetric Analysis | Mass of inorganic residue remaining after high-temperature ashing at 750 C in a muffle furnace. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Hydrogen ion activity measured using calibrated glass electrode in aqueous suspension. |
| Appearance (Color and Clarity) | Visual Inspection | Assessment under controlled white light against standard color references (e.g., APHA scale) and against clear water blank. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volume-based particle size distribution. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 146°C |
| Optical Rotation | +18.5° to +19.5° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.