2-CHLORO-5-FLUOROISONICOTINIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 884494-74-0 |
| Product name | 2-CHLORO-5-FLUOROISONICOTINIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-5-FLUOROISONICOTINIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-5-FLUOROISONICOTINIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-5-FLUOROISONICOTINIC ACID
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of novel herbicide intermediates | Chlorination and fluorination of the nicotinic acid scaffold to introduce chloro- and fluoro-substituents for constructing high-efficacy, selective herbicide molecules |
| Pharmaceuticals | Drug synthesis intermediate for developing anti-inflammatory or antitumor agents | Organic synthesis pathways—including coupling and amidation reactions—to construct core structural units of complex drug molecules |
| Polymers | Monomer or modifier for functional polymers | Esterification or amidation to incorporate into polymer chains, enhancing thermal stability or biocompatibility |
| Fine Chemicals | Raw material for specialty chemicals, including dyes and photosensitive materials | Coupling or oxidation reactions under specific catalysis to produce compounds with targeted optical properties |
Manufacturing Quality Control of 2-CHLORO-5-FLUOROISONICOTINIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 220-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, DMF) against calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other toxic metals after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to calculate volume-based particle size distribution (D10, D50, D90). |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized mechanical tapping per ASTM D1895. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Optical Rotation | Polarimetry | Determination of specific rotation using sodium D-line light source in solution, indicating chiral purity or absence of enantiomeric impurities. |
Technical Specifications of 2-CHLORO-5-FLUOROISONICOTINIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-5-FLUOROISONICOTINIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-5-FLUOROISONICOTINIC ACID
Safety Information of 2-CHLORO-5-FLUOROISONICOTINIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-CHLORO-5-FLUOROISONICOTINIC ACID
Industrial 2-CHLORO-5-FLUOROISONICOTINIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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