China Factory Direct
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| CAS number | 884494-84-2 |
| Product name | 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical & Fine Chemicals | Organic synthesis intermediate | Used to construct drug molecule scaffolds containing fluorinated pyridine or iodopyridine moieties. |
| Pharmaceutical & Fine Chemicals | Cross-coupling reaction substrate | Enables introduction of aryl, vinyl, or alkynyl groups via palladium-catalyzed coupling reactions—such as Suzuki, Stille, or Sonogashira—leveraging the reactivity of the iodine atom. |
| Pharmaceutical & Fine Chemicals | Drug discovery building block | Applied in the design and synthesis of novel bioactive molecules, particularly for lead compound screening in agrochemical and pharmaceutical development. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by retention time and UV response relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., methanol, dichloromethane) via capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion using inductively coupled plasma mass spectrometry. |
| Iodine Content | Potentiometric Titration | Determines total iodine by oxidation to iodate followed by iodometric back-titration with sodium thiosulfate. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups by titration with standardized NaOH using phenolphthalein indicator. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determines solid-phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of crystalline solid against white/black background under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie scattering theory and optical diffraction pattern analysis. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature ignition (700-800 C) followed by precise weighing of residual residue. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112-116°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.