3-Amino-2-bromo-5-fluoropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 884495-03-8 |
| Product name | 3-Amino-2-bromo-5-fluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Amino-2-bromo-5-fluoropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Amino-2-bromo-5-fluoropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Amino-2-bromo-5-fluoropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antitumor drug intermediates | Used as a key intermediate for constructing fluorinated pyridine compounds, participating in coupling or nucleophilic substitution reactions |
| Agrochemical R&D | Synthesis intermediate for insecticides/fungicides | Applied in the preparation of novel fluorinated heterocyclic agrochemical active ingredients, with functional group transformation enabled by the bromine atom |
| Organic Synthesis | Building block for fluorinated pyridine compound synthesis | Leverages dual functionality of the amino and bromo groups for selective modification and coupling reactions |
Manufacturing Quality Control of 3-Amino-2-bromo-5-fluoropyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., regioisomers, dehalogenated by-products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., DMF, dichloromethane, methanol) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Pd) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Residual Palladium | ICP-OES | Quantification of residual Pd catalyst from synthesis via microwave-assisted acid digestion followed by plasma emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; sharp melting range indicates crystalline purity and absence of eutectic impurities. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at specified wavelength (e.g., 589 nm) and temperature to assess chiral integrity (though compound is achiral, detects chiral contaminants). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via light scattering to determine D10, D50, D90 values relevant for downstream processing and formulation. |
| Bulk and Tapped Density | ASTM D6393 (Tap Density Tester) | Mechanical tapping of a known mass in a graduated cylinder to determine volumetric density parameters critical for flowability and dosing accuracy. |
| Microbial Limits | Membrane Filtration + Culture-Based Enumeration | Sterile filtration followed by growth on selective media (TSA, SDA) to enumerate aerobic bacteria and fungi per pharmacopeial limits (if applicable to pharma-grade material). |
Technical Specifications of 3-Amino-2-bromo-5-fluoropyridine
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Amino-2-bromo-5-fluoropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Amino-2-bromo-5-fluoropyridine
Safety Information of 3-Amino-2-bromo-5-fluoropyridine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-Amino-2-bromo-5-fluoropyridine
Industrial 3-Amino-2-bromo-5-fluoropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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