China Factory Direct
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| CAS number | 884495-39-0 |
| Product name | 5-BROMO-2-METHOXY-3-CYANOPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of antitumor agents (e.g., BTK inhibitors) and antimicrobial drugs | Serves as a brominated heterocyclic building block in coupling reactions (e.g., Suzuki, Heck), where aryl or alkenyl groups are introduced via palladium catalysis; methoxy and amino groups undergo selective protection/deprotection to enable multistep functionalization |
| Agrochemicals | Used to construct the heterocyclic core structures of novel insecticides and fungicides | Triazine- or pyrimidine-based agrochemical molecules are assembled via nucleophilic substitution or cyclization reactions; the bromine atom provides a site for subsequent derivatization |
| Materials Science | Used as a precursor for electron-transport layer materials in organic light-emitting diodes (OLEDs) | Hole-transport moieties (e.g., carbazole, triphenylamine) are introduced via Ullmann or Buchwald–Hartwig coupling to form thermally stable conjugated small molecules |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by retention time and UV response relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) via headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent in anhydrous methanol. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after charring at 700-800 C and weighing the ash. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of crystalline solid against standard white background under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light in solution to confirm chiral integrity and absence of racemization. |
| pH of Aqueous Suspension | pH Meter | Evaluates acidity/basicity of saturated aqueous suspension using calibrated pH electrode per EP 2.2.3. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of dry powder using Mie scattering theory with automated dispersion and analysis. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.