China Factory Direct
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| CAS number | 88466-74-4 |
| Product name | (S)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral intermediate for synthesizing biologically active pharmaceutical molecules, such as antiviral or neurologically active compounds | Critical building block in multistep organic synthesis; commonly employed in asymmetric synthesis or protecting-group strategies to introduce the piperidine moiety |
| Organic Synthesis | Chiral building block for constructing complex molecules containing a piperidine ring | Subject to downstream modifications, including ester hydrolysis, debenzylation, or amine functional group transformations |
| Agrochemical R&D (Potential) | Potential use in developing novel chiral pesticides or plant growth regulators (based on known bioactivity of piperidine-containing compounds) | Serves as a structural template in lead compound optimization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, calibrated against certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation on a chiral stationary phase with UV detection; ee calculated from peak area ratio of (S)- and (R)-enantiomers. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., toluene, ethyl acetate) against external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-MS | Multi-element detection after acid digestion; quantifies Pb, Cd, Hg, As, and other regulated metals at trace levels. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride quantified via calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Sample incinerated at 500-600 C, residue treated with sulfuric acid and re-ignited; ash weight expressed as % w/w. |
| Related Substances | HPLC-UV | Forced degradation study coupled with stability-indicating HPLC method to identify and quantify structurally related impurities. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; specific rotation calculated per USP/Ph. Eur. guidelines. |
| Residual Palladium | ICP-OES | After microwave-assisted acid digestion, Pd quantified by optical emission spectroscopy at characteristic wavelength (247.64 nm). |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to determine volume-based particle size distribution in dispersed slurry. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 132°C |
| Optical Rotation | +24.0° to +26.0° (c=1, in methanol) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.