China Factory Direct
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| CAS number | 885168-20-7 |
| Product name | 2-BROMO-5-FLUORO-4-PICOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor or antiviral active molecules | Active functional groups are introduced via coupling, fluorination, or bromination reactions |
| Agrochemicals | Used as an intermediate for synthesizing fluorinated pyridine-based insecticides or fungicides | Condensation with sulfides or amines to construct heterocyclic structures |
| Materials Science | Used as a monomer for synthesizing fluorinated optoelectronic or liquid crystal display materials | Cross-coupling reactions (e.g., Suzuki coupling) to build conjugated systems |
| Organic Synthesis | Used as a versatile building block in C–C and C–N bond-forming reactions | Arylation or amination reactions catalyzed by transition metals (e.g., palladium) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., isomers, dehalogenated by-products) via gradient HPLC with UV detection and relative response factor correction. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., dichloromethane, toluene) using headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine-methanol buffer. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Quantifies elemental impurities at sub-ppb levels using inductively coupled plasma mass spectrometry after acid digestion and matrix-matched calibration. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue by ignition at 700-800 C and weighing the residual ash after cooling in a desiccator. |
| Melting Point | Capillary Melting Point Apparatus | Determines purity-dependent solid-to-liquid transition temperature range using calibrated capillary method per USP <741>. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to detect chiral impurities or enantiomeric excess (though compound is achiral, verifies absence of chiral contaminants). |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering intensity of laser light through dispersed sample. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 10% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies unspecified volatile organic impurities using gas chromatography coupled with mass spectrometric detection and library matching. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.