6-BROMO-3-CHLORO-1H-INDAZOLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 885271-78-3 |
| Product name | 6-BROMO-3-CHLORO-1H-INDAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-BROMO-3-CHLORO-1H-INDAZOLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-BROMO-3-CHLORO-1H-INDAZOLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-BROMO-3-CHLORO-1H-INDAZOLE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing kinase inhibitor–based anticancer drugs (e.g., BTK inhibitors) | Under inert atmosphere: Suzuki coupling with arylboronic acids; or nucleophilic substitution with amines to construct the target molecular scaffold |
| Agrochemical R&D | Lead compound for developing novel insecticides and fungicides | Functional group introduction via nitrogen alkylation or halogen substitution on the ring to optimize biological activity |
| Materials Science | Building block for synthesizing organic optoelectronic materials, including indazole-based fluorescent dyes | Palladium-catalyzed Sonogashira coupling with alkynes to construct conjugated luminescent scaffolds |
Manufacturing Quality Control of 6-BROMO-3-CHLORO-1H-INDAZOLE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., regioisomers, dehalogenated by-products) via gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, methanol) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As) after acid digestion by measuring elemental mass-to-charge ratios with high sensitivity and multi-element capability. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Measures palladium from catalytic hydrogenation residues after microwave-assisted acid digestion and plasma optical emission detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of phase change. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration against established reference standards under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying at specified temperature (e.g., 105 C) for fixed duration under vacuum or nitrogen. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by measuring angular variation in laser light scattering intensity. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light through a solution in specified solvent and path length to confirm chiral integrity if applicable. |
Technical Specifications of 6-BROMO-3-CHLORO-1H-INDAZOLE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 148-152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-BROMO-3-CHLORO-1H-INDAZOLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-BROMO-3-CHLORO-1H-INDAZOLE
Packaging of 6-BROMO-3-CHLORO-1H-INDAZOLE
Industrial 6-BROMO-3-CHLORO-1H-INDAZOLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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