6-BROMO-4-NITRO-1H-INDAZOLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 885518-46-7 |
| Product name | 6-BROMO-4-NITRO-1H-INDAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-BROMO-4-NITRO-1H-INDAZOLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-BROMO-4-NITRO-1H-INDAZOLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-BROMO-4-NITRO-1H-INDAZOLE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for small-molecule kinase inhibitors | Used in the synthesis of BTK (Bruton’s tyrosine kinase) and FLT3 (FMS-like tyrosine kinase 3) targeted inhibitors; aryl/heteroaryl substituents are introduced via palladium-catalyzed cross-coupling (e.g., Suzuki or Heck reactions), followed by reduction and cyclization to construct the core structure of the final product |
| Agrochemical R&D | Building block for novel insecticidal lead compounds | Serves as a nitrogen-containing heterocyclic pharmacophore module; incorporated into pyrethroid or neonicotinoid scaffolds via N1-alkylation and C3 functional group transformation to optimize binding activity toward insect sodium ion channels or nicotinic acetylcholine receptors |
| Materials Science | Precursor for hole-transport layer dopants in organic electroluminescent (OLED) devices | After selective metalation of the bromine atom (using n-BuLi at low temperature), coupled with boronic esters to synthesize indazole-based conjugated small molecules exhibiting high glass transition temperature and suitable HOMO energy level, for vacuum thermal evaporation deposition |
Manufacturing Quality Control of 6-BROMO-4-NITRO-1H-INDAZOLE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation to determine water content via stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion by atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity-based quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration and weighing of residual material. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Bulk Density | USP <616> Tap Density Method | Measurement of mass per unit volume after standardized tapping of a powder sample in a calibrated cylinder. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular scattering pattern of laser light passed through a dispersed sample. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using plane-polarized light to assess chiral purity and enantiomeric excess. |
Technical Specifications of 6-BROMO-4-NITRO-1H-INDAZOLE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-BROMO-4-NITRO-1H-INDAZOLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-BROMO-4-NITRO-1H-INDAZOLE
Packaging of 6-BROMO-4-NITRO-1H-INDAZOLE
Industrial 6-BROMO-4-NITRO-1H-INDAZOLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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