2-Bromo-5-fluoroisonicotinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 885588-12-5 |
| Product name | 2-Bromo-5-fluoroisonicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-5-fluoroisonicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-5-fluoroisonicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-5-fluoroisonicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents (e.g., EGFR inhibitors) | Constructing pyridine ring side chains via Suzuki coupling, amination, or esterification |
| Pesticides | Active ingredient in novel fluorinated insecticides and herbicides | Acyl chloride formation followed by condensation with amines to introduce specific substituents |
| Materials Science | Building block for electron-transport layer materials in organic light-emitting diodes (OLEDs) | Integration into conjugated polymer backbones via palladium-catalyzed cross-coupling reactions |
Manufacturing Quality Control of 2-Bromo-5-fluoroisonicotinic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, condition, and presence of visible foreign substances under natural light or standard light source. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase C18 column with a gradient elution of water-organic solvent (e.g., acetonitrile/methanol), detection by UV detector (usually at 254 nm). The content of the main component is calculated using peak area normalization or external standard method. |
| Related Substances (Impurities) | HPLC Method | Same as purity testing. Detect and quantify various organic impurities (e.g., starting materials, intermediates, degradation products) by comparing with known impurity reference standards or self-dilution method (dilution of the main component itself). |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, use headspace GC to detect residual organic solvents (e.g., methanol, ethanol, dichloromethane, ethyl acetate) from the production process. |
| Moisture | Karl Fischer Titration | Determine moisture content quantitatively using Karl Fischer reagent, suitable for precise measurement of trace moisture. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting using a melting point apparatus, used for identification and evaluation of compound purity. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), Infrared Spectroscopy (IR) | Confirm molecular structure using methods such as ¹H-NMR, ¹³C-NMR, LC-MS, and FT-IR to verify the chemical structure of the target compound. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectrometry (AAS) | Detect heavy metal residues such as lead, arsenic, cadmium, and mercury, complying with pharmacopoeia or relevant regulatory limit requirements. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | Determine the amount of inorganic residue after high-temperature incineration of the sample, used to evaluate the content of inorganic impurities. |
| Content Determination | HPLC External Standard Method | Prepare a standard curve using a standard solution of known concentration, and determine the absolute content of the main component in the sample using HPLC, commonly used for quantitative analysis of active pharmaceutical ingredients. |
Technical Specifications of 2-Bromo-5-fluoroisonicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142-146°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-5-fluoroisonicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-5-fluoroisonicotinic acid
Safety Information of 2-Bromo-5-fluoroisonicotinic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Bromo-5-fluoroisonicotinic acid
Industrial 2-Bromo-5-fluoroisonicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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