FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 885951-77-9 |
| Product name | FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Amino acid protecting reagent in solid-phase peptide synthesis (SPPS) | Used as an Nα-protecting group to reversibly protect the amino group of 1-amino-1-cyclobutanecarboxylic acid via the Fmoc moiety, enabling synthesis of therapeutic peptides or peptide drug intermediates containing a cyclobutylglycine motif |
| Biochemical Research | Conformationally constrained non-natural amino acid monomer | Participates in coupling reactions after piperidine-mediated deprotection during peptide chain elongation, introducing a rigid cyclobutane scaffold to modulate peptide secondary structure, metabolic stability, and target-binding specificity |
Manufacturing Quality Control of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., DMF, DCM, methanol) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Ni, Cu) by inductively coupled plasma mass spectrometry after acid digestion. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to assess inorganic ash content. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using laser scattering to determine D10, D50, D90 values. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually or automatically. |
| Microbial Contamination | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms via filtration, membrane transfer to culture media, and colony counting after incubation. |
Technical Specifications of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -15.0 to -19.0° (c=1, DMF) |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
Safety Information of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID
Industrial FMOC-1-AMINO-1-CYCLOBUTANECARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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