3-BROMO-6-CHLORO-2-FLUOROPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 885952-18-1 |
| Product name | 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel insecticides, used in synthesizing neonicotinoid insecticides (e.g., flupyradifurone analogues) | Undergoes nucleophilic substitution with amines to construct fluorinated pyridine heterocyclic structures |
| Pharmaceuticals | Key intermediate for anticancer agents and kinase inhibitors | Participates in cross-coupling reactions, including Suzuki coupling and Buchwald–Hartwig amination |
| Materials Science | Structural building block for organic optoelectronic materials (e.g., dopants in OLED emissive layers) | Introduces conjugated side chains via halogen exchange or metal-catalyzed coupling to tune energy levels and charge-carrier transport properties |
Manufacturing Quality Control of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time comparison and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion and dilution, per ICH Q3D. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue following microwave-assisted acid digestion and analysis by inductively coupled plasma optical emission spectrometry. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Loss on Drying | Gravimetric Analysis | Mass loss determination after drying at specified temperature (e.g., 105 C) for fixed duration under vacuum or air. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to detect acidic degradation products. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry or dispersed particle size via light scattering pattern analysis using Mie theory. |
Technical Specifications of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
Safety Information of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE
Industrial 3-BROMO-6-CHLORO-2-FLUOROPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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