5-Bromo-2-chloroisonicotinic acid Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 886365-31-7 |
| Product name | 5-Bromo-2-chloroisonicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 5-Bromo-2-chloroisonicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-2-chloroisonicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-2-chloroisonicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antiviral agents and kinase inhibitors | Used to construct the core drug structure via amidation or esterification of 5-bromo-2-chloroisonicotinic acid with amines or alcohols |
| Agrochemicals | Intermediate for synthesizing novel insecticides or fungicides | Applied in nucleophilic substitution or coupling reactions to introduce nitrogen-containing heterocyclic structures, enhancing biological activity |
| Chemical Research | Organic building block for constructing halogenated heterocyclic compounds | Employed in cross-coupling reactions—including Suzuki and Buchwald-Hartwig—to prepare functionalized isonicotinic acid derivatives |
Manufacturing Quality Control of 5-Bromo-2-chloroisonicotinic acid
| Test Item | Common Test Method | Method Description |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with a reference spectrum to confirm the presence of characteristic functional groups (e.g., carboxyl, halogen-substituted aromatic rings), used for structural confirmation of compounds. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Uses nuclear magnetic resonance technology to analyze chemical shifts, coupling constants, and integration areas of hydrogen atoms in the sample. Comparison with theoretical spectra verifies the structure of the target compound. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employs a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and UV detection (typically around 254 nm). The assay quantifies the main component using external or internal standard methods, offering high sensitivity and good reproducibility. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Similar to the assay method, but with optimized chromatographic conditions to achieve good separation between the main peak and potential impurities (e.g., starting materials, intermediates, degradation products). Impurities are quantified using area normalization or a corrected main-component self-reference method. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Weight Method | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved. The percentage weight loss is calculated to assess moisture and volatile content. |
| Sulfated Ash / Residue on Ignition | Gravimetric Method | The sample is ignited at high temperature (typically 700–800°C), and the remaining inorganic residue is weighed to control inorganic impurities or residual metal catalysts. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection, with capillary columns for separation and FID detection. According to the Chinese Pharmacopoeia or ICH Q3C guidelines, this method performs qualitative and quantitative analysis of organic solvents potentially remaining from synthesis (e.g., methanol, dichloromethane, DMF). |
| Halogen Content (Bromine/Chlorine) | Ion Chromatography (IC) or Oxygen Flask Combustion-Titration Method | Organically bound halogens are converted into inorganic ions via oxygen flask combustion, followed by determination of bromide and chloride ions using ion chromatography or argentometric titration, verifying that elemental composition meets expectations. |
Technical Specifications of 5-Bromo-2-chloroisonicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 172-176°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 5-Bromo-2-chloroisonicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-2-chloroisonicotinic acid
Safety Information of 5-Bromo-2-chloroisonicotinic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Bromo-2-chloroisonicotinic acid
Industrial 5-Bromo-2-chloroisonicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply