4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 886372-03-8 |
| Product name | 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as building blocks for synthesizing anticancer drug candidates, such as BTK inhibitors | Employed as aryl halide components in palladium-catalyzed cross-coupling reactions (e.g., Suzuki or Heck reactions) to form C–C bonds |
| Agrochemical R&D | Serves as a key structural unit in novel insecticidal and fungicidal molecules | Undergoes functional group transformations—such as aminolysis, hydrolysis, or reduction—to introduce heterocyclic side chains that enhance biological activity |
| Organic Synthesis | Highly selective arylating reagent for constructing functional molecules containing pyridine scaffolds | Undergoes nucleophilic addition with organolithium or Grignard reagents at low temperature, followed by oxidation or substitution to yield polysubstituted pyridine derivatives |
Manufacturing Quality Control of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by HPLC with UV detection, using gradient elution and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection of trace metals after acid digestion, using inductively coupled plasma mass spectrometry for high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after anion exchange chromatography. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing and weighing of the remaining solids. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually under controlled heating rate. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral molecules in solution at specified concentration and path length. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to calculate particle size distribution based on Mie theory. |
| Bulk Density | USP <616> Tap Density Method | Determination of mass per unit volume after mechanical tapping of a powder sample in a standardized cylinder. |
| Microbial Limits | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms by filtration, membrane transfer to culture media, and colony counting. |
Technical Specifications of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
Safety Information of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER
Industrial 4-BROMO-6-METHYL-NICOTINIC ACID METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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