China Factory Direct
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| CAS number | 886499-88-3 |
| Product name | 2-BROMO-4-CHLORO-6-FLUOROPHENOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key structural unit in the synthesis of active pharmaceutical ingredients (APIs) containing multiple halogen substituents. |
| Agrochemicals | Agrochemical Intermediates | Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its halogenated structure to optimize biological activity. |
| Organic Synthesis | Specialty Organic Synthesis Reagents | Enables construction of complex aromatic frameworks via cross-coupling reactions—including Suzuki coupling and Buchwald–Hartwig amination—by exploiting the differential reactivity of bromine, chlorine, and fluorine. |
| Materials Science | Functional Material Monomers | Applied in the synthesis of fluorinated aromatic polymers or OLED material intermediates, where fluorine incorporation enhances thermal stability and hydrophobicity. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching with reference standards or relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic mass spectrometry for sub-pptr sensitivity. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride anion in aqueous extract; quantified against NaCl calibration curve. |
| Acidity (Free Acid) | Acid-Base Titration | Neutralization of acidic impurities with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid sample against established reference under controlled lighting and white background. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying sample at 105 C for 2 hours under vacuum or nitrogen purge, per USP <731>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Residue on Ignition | Gravimetric Ashing | Measurement of non-volatile inorganic residue after ignition at 600-700 C for 1 hour, followed by cooling and weighing. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72–76 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.