China Factory Direct
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| CAS number | 886762-75-0 |
| Product name | 4-BROMO-3-FLUORO-2-NITROANILINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor agents and selective kinase inhibitors | Produced via multi-step aromatic electrophilic substitution and reduction, starting from 2-nitro-3-fluoro-4-bromobenzene with selective nitro group reduction |
| Agrochemicals | Intermediate for synthesizing novel fluorinated aniline-based fungicides and insecticides | Selective nitro-to-amino reduction under catalytic conditions, followed by coupling with fluorinated heterocyclic compounds to construct the active molecule |
| Dyes & Pigments | Diazonium component for high-stability azo dyes | Diazotized under low-temperature acidic conditions, then coupled with phenolic or amine coupling agents to form colored compounds |
| Electronic Materials | Precursor for high-performance organic semiconductors or OLED materials | Aryl or heteroaryl groups introduced via palladium-catalyzed cross-coupling to construct conjugated π-systems |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; total heavy metals (Pb, Cd, Hg, As) reported as ppm against USP <231> limits. |
| Residual Inorganic Salts | Ion Chromatography (IC) | Quantification of anions (Cl-, SO42-, NO3-) and cations (Na+, K+, NH4+) following aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature range using calibrated digital melting point instrument per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standard. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum, indicating volatile and moisture content. |
| Chloride Impurity | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode to detect chloride ions from side reactions or hydrolysis. |
| pH of Aqueous Suspension | pH Meter Measurement | pH measurement of 1% w/v suspension in purified water using calibrated pH meter to assess acidic/basic degradation products. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized tapping to evaluate powder flow and handling properties. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.