China Factory Direct
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| CAS number | 887266-99-1 |
| Product name | 3-FLUORO-4-IODOBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key aryl iodide building block for synthesizing kinase inhibitor–based anticancer drugs (e.g., BTK inhibitors) | Introduces fluorinated aryl structures via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) |
| Agrochemical R&D | Structural unit for synthesizing fluorine- and iodine-containing heterocyclic insecticides and fungicides | Constructs active molecular cores via halogen exchange or transition metal–catalyzed cyclization |
| Materials Science | Precursor for electron transport layer materials in organic light-emitting diodes (OLEDs) | Builds conjugated small molecules or polymer backbones via cyanide-involved addition/condensation reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 220 nm. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection, using headspace sampling. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration | Volumetric determination of water based on stoichiometric iodine reaction with sulfur dioxide and pyridine in methanol medium. |
| Residual Iodine (as I2 or HI) | Redox Titration with Sodium Thiosulfate | Oxidizable iodine species titrated with standardized Na2S2O3 solution using starch indicator for endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine size distribution of dry powder sample in accordance with ISO 13320. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-DAD | Identification and quantification of structurally related impurities (e.g., 3-fluoro-4-iodobenzamide, des-iodo analog) using diode array detection and retention time matching. |
| Appearance (Color & Clarity) | Visual Inspection | Comparison of sample solution (in acetonitrile) against APHA color standard and visual assessment of clarity per EP 2.2.1. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a 1% w/v suspension in purified water using calibrated pH electrode per USP <791>. |
| Test Item | Specification |
|---|---|
| Appearance | Purple solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 118–122°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.