China Factory Direct
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| CAS number | 887583-90-6 |
| Product name | 4-BROMO-2-TRIFLUOROMETHYLPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors (e.g., BTK inhibitors) | Used as a key aryl halogenated heterocyclic building block in palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Buchwald–Hartwig couplings |
| Agrochemical R&D | Structural modification and lead compound optimization for novel insecticides and fungicides | Employed to introduce trifluoromethyl and bromo substituents—enhancing lipophilicity, metabolic stability, and target binding affinity—in the construction of pyridine-containing agrochemical active molecules |
| Materials Science | Synthesis of functional small molecules for hole-transport or electron-transport layers in organic light-emitting diodes (OLEDs) | Utilized for halogen exchange or coupling reactions via the bromo group to install conjugated side chains, thereby tuning HOMO/LUMO energy levels and charge-carrier mobility |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., starting materials, intermediates, dehalogenated by-products) using gradient HPLC-UV with suitable column and mobile phase. |
| Residual Solvents | GC-FID | Identifies and quantifies common organic solvents (e.g., dichloromethane, toluene, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Inorganic Halides (e.g., Br-) | Ion Chromatography (IC) | Separates and quantifies bromide and other halide ions using anion-exchange column with conductivity detection. |
| Heavy Metals | ICP-OES | Measures total elemental impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic residue after high-temperature ashing (600-750 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against defined standards under controlled lighting conditions. |
| Chloride Content | Potentiometric Titration | Quantifies chloride ions using silver nitrate titrant and silver/silver chloride electrode for endpoint detection. |
| Bulk Density | ASTM D1895 | Determines mass per unit volume of freely settled powder using standardized cylinder and balance. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using angular scattering pattern of laser beam. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/4°C) | 1.62–1.66 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.