China Factory Direct
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| CAS number | 88950-64-5 |
| Product name | 1-(Boc-amino)cyclopropanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key pharmaceutical intermediate | Used in the synthesis of chiral drugs or active pharmaceutical ingredients (APIs) containing cyclopropyl motifs. |
| Pharmaceutical Chemicals | Peptide and protein drug synthesis | Incorporated as an amino acid monomer bearing a cyclopropyl group; Boc deprotection under acidic conditions enables solid-phase or solution-phase peptide synthesis. |
| Chemical R&D | Asymmetric synthesis and stereochemical research | Leverages the steric hindrance of the cyclopropane ring to achieve stereoselective reactions or construct molecular scaffolds with defined stereochemistry. |
| New Drug Discovery | Drug molecule building block | Employed in Suzuki coupling, amidation, and related reactions to construct lead compound libraries containing the cyclopropylglycine motif. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching and/or spiked reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) via headspace GC with flame ionization detection using calibrated external standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation using a polarimeter at 20 C and 589 nm to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Ni) after acid digestion by detecting elemental isotopes via inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by precise weighing of residual non-volatile matter. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines pH of 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering pattern of laser light passed through dispersed sample. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) using selective agar media and incubation per pharmacopeial guidelines. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method under controlled heating rate. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +12.0 to +16.0° (c=1, in 1M HCl) |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.