China Factory Direct
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| CAS number | 889670-02-4 |
| Product name | (R)-METHYL 2-(TERT-BUTOXYCARBONYLAMINO)-3-IODOPROPANOATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the synthesis of Boc-protected amino acid derivatives as pharmaceutical intermediates | Organic synthesis; protecting group reactions |
| Biochemistry | Applied as a modifying reagent in protein or peptide synthesis | Solid-phase peptide synthesis |
| Research & Development | Used to investigate the mechanistic role of iodoamino acids in biologically active molecules | Laboratory-scale synthesis |
| Test Item | Common Testing Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of foreign matter under natural or standard lighting; it should be white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) |
IR: Record the infrared absorption spectrum of the sample and compare characteristic absorption peaks with those of a reference standard or official spectrum. ¹H NMR: Confirm molecular structural features based on chemical shifts, integration areas, and coupling constants. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detect using a UV detector (typically at 210–230 nm) and quantify the main component by external or internal standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar conditions as assay, but with optimized gradient elution to separate potential impurities (e.g., starting materials, by-products, degradation products). Impurity levels are calculated using area normalization or a main-component self-dilution control method with correction factors. |
| Water Content | Karl Fischer Titration | Quantitatively determine water content based on the reaction of iodine with sulfur dioxide in the presence of pyridine/imidazole, using either coulometric or volumetric titration methods. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection onto a polar or nonpolar capillary column, with FID detection. Test for residual organic solvents (e.g., dichloromethane, methanol, DMF) from synthesis according to ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Method | Pack sample into a capillary tube and heat at a specified rate in a melting point apparatus. Record the temperature range from initial melting to complete melting and compare with the standard value. |
| Specific Optical Rotation | Polarimetry | Prepare a solution of defined concentration and measure optical rotation at a specified wavelength (usually sodium D line, 589 nm) and temperature. Calculate specific optical rotation to assess optical purity. |
| pH (if dissolved in solution) | pH Meter Method | Dissolve the sample into an aqueous or suitable solvent system at a specified concentration and measure acidity/alkalinity using a calibrated pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 75-79°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in CHCl3) |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.