5-Aminosalicylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 89-57-6 |
| Product name | 5-Aminosalicylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Aminosalicylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Aminosalicylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Aminosalicylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Therapeutic agent for ulcerative colitis | Used as an active pharmaceutical ingredient (API) in oral immediate-release or extended-release formulations to selectively inhibit inflammatory mediators at the site of colonic inflammation. |
| Pharmaceutical Industry | Therapeutic agent for Crohn’s disease | Administered orally or via enema as the primary pharmacologically active component to alleviate symptoms of segmental ileitis and Crohn’s disease. |
| Pharmaceutical Industry | Intermediate in drug synthesis | Serves as a key synthetic intermediate in coupling reactions to prepare prodrugs (e.g., olsalazine, balsalazide) or in salt formation reactions to synthesize mesalazine derivatives. |
| Chemical Industry | Organic synthesis intermediate | Reacted with diazonium salts in azo coupling reactions to produce azo dyes; alternatively used as a starting material for synthesizing other salicylic acid derivatives. |
| Research Field | Biochemical research reagent | Functions as a ligand and agonist of peroxisome proliferator-activated receptor gamma (PPAR-γ), employed in studies of cellular signaling pathways and anti-inflammatory mechanisms. |
Manufacturing Quality Control of 5-Aminosalicylic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes characteristic absorption peaks of 5-ASA at specific wavelengths (e.g., around 265 nm and 330 nm) for qualitative identification. |
| Infrared Spectroscopy (IR) | Confirms the presence of functional groups (e.g., —NH₂, —COOH, phenolic hydroxyl) by comparing the sample's infrared absorption spectrum with a reference spectrum. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 column and UV detector (around 265 nm), with methanol-water or buffered solutions as mobile phase, for accurate quantification. |
| Ultraviolet Spectrophotometry (UV) | Measures absorbance at the maximum absorption wavelength and calculates concentration using a standard curve; suitable for samples with high purity. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separates the main component from impurities (e.g., 4-aminosalicylic acid, azo impurities) using gradient or isocratic elution to assess purity. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, acetone) to ensure compliance with pharmacopoeial requirements. |
| Water Content | Karl Fischer Titration | Accurately determines water content in the sample; commonly used in quality control of active pharmaceutical ingredients (APIs). |
| Melting Point | Melting Point Determination | Measures the melting temperature using a melting point apparatus (literature value approximately 149–151 °C) for preliminary assessment of purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determines residual heavy metal elements such as lead, cadmium, and mercury to ensure compliance with pharmaceutical safety limits. |
| Solution Clarity and Color | Visual Comparison or Spectrophotometry | Prepares a solution of the sample and evaluates its clarity and color against specified standards, indicating the presence of insoluble particles or colored impurities. |
| Loss on Drying | Thermogravimetric Analysis or Oven Drying Method | Determines weight loss after drying under specified conditions to assess levels of volatile components or adsorbed water. |
| Sulfated Ash (Residue on Ignition) | Residue on Ignition Test | Weighs the residue after high-temperature incineration to estimate inorganic impurity content. |
Technical Specifications of 5-Aminosalicylic acid
| Test Item | Specification |
|---|---|
| Appearance | White to gray or reddish crystalline powder |
| Purity | >=98.5% (HPLC) |
| Melting Point | 193–197 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Aminosalicylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Aminosalicylic acid
Packaging of 5-Aminosalicylic acid
Industrial 5-Aminosalicylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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