Copper tripeptide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 89030-95-5 |
| Product name | Copper tripeptide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Copper tripeptide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Copper tripeptide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Copper tripeptide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Wound healing promotion | Used in the preparation of drugs or topical formulations designed to support skin repair and regeneration |
| Beauty & Cosmetics | Anti-aging | Incorporated into skincare products to help reduce fine lines and improve skin firmness |
| Beauty & Cosmetics | Repair of damaged skin | Applied in masks, serums, and similar products to accelerate skin cell regeneration |
| Medical Devices | Tissue repair promotion | Formulated as an active ingredient in certain medical dressings for adjunctive treatment of chronic ulcers |
| Biotechnology | Cell culture additive | Added to cell culture media to support cell growth and proliferation |
Manufacturing Quality Control of Copper tripeptide
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with water-acetonitrile gradient elution and UV detection (210–220 nm) to detect the main peak of GHK-Cu. The area percentage of the main peak is calculated to assess purity (typically requiring ≥95%). |
| Content Determination | HPLC-UV or HPLC-MS | Quantitative analysis of GHK-Cu in samples using external standard or internal standard method, establishing calibration curves with reference standards. HPLC-MS improves specificity by eliminating interference from structurally similar impurities. |
| Heavy Metal Content (Cu²⁺) | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, copper ion concentration is determined via AAS or trace copper quantified using ICP-MS, ensuring a 1:1 molar ratio of Cu:GHK and excluding free copper contamination. |
| Peptide Sequence Confirmation | Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Verifies the correct tripeptide sequence (Gly-His-Lys) and copper coordination structure by comparing experimental MS/MS fragmentation patterns with theoretical fragment ions (e.g., m/z 258, 315, 372). |
| Moisture Content | Karl Fischer Titration | Utilizes iodine-sulfur dioxide-pyridine-methanol system for quantitative reaction with water, measuring residual moisture; controlled to ≤3% to prevent degradation or microbial growth. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection, detects organic solvent residues such as ethanol, acetone, dichloromethane, conforming to ICH Q3C guidelines to ensure complete removal of process solvents. |
| Related Substances (Impurity Profile) | HPLC-UV or HPLC-MS | Establishes gradient elution methods to detect degradation products (e.g., des-copper GHK, oxidized forms, dimers), with specifications limiting single impurity ≤0.5% and total impurities ≤1.0%. |
| UV-Visible Absorption Spectra | UV-Vis Spectrophotometry | Measures characteristic absorption peaks at 225 nm (peptide bond) and 280 nm (histidine imidazole ring) to confirm coordination structure and concentration (molar extinction coefficient ε ≈ 5,000 M⁻¹cm⁻¹). |
| pH Value | pH Meter Measurement | Prepared as aqueous solution (e.g., 1 mg/mL), measured at 25°C, typically controlled within range 5.0–6.5 to ensure stability and biocompatibility. |
| Total Heavy Metals | ICP-MS or Chinese Pharmacopoeia Heavy Metal Test Method | Determined according to pharmacopoeial methods (e.g., thioacetamide method) or ICP-MS to detect lead, cadmium, mercury, arsenic, etc., ensuring compliance with pharmaceutical-grade standards (e.g., ≤10 ppm). |
| Microbial Limits | Microbial Count and Control Organism Tests | Conducted per Chinese Pharmacopoeia or USP methods to test total aerobic bacteria, mold and yeast, Escherichia coli, Staphylococcus aureus, etc., ensuring sterility or meeting non-sterile dosage form requirements. |
| Stability (Accelerated Testing) | HPLC + Moisture + pH Monitoring Over Time | Stored under 40°C/75% RH conditions, with periodic testing of active ingredient content, impurity profile, moisture, and pH to evaluate chemical and physical stability during storage. |
Technical Specifications of Copper tripeptide
| Test Item | Specification |
|---|---|
| Appearance | Blue Solid |
| Purity | ≥99.0% |
| Purity | 8.0%~16.0% |
| Loss on drying | ≤8.0% |
| Chloride | ≤10.0% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Copper tripeptide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Copper tripeptide
Packaging of Copper tripeptide
Industrial Copper tripeptide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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