China Factory Direct
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| CAS number | 892493-65-1 |
| Product name | 4-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediate | Used in organic synthesis for constructing piperidine derivatives |
| Chemical manufacturing | Chemical reagent | Involved in multistep organic reactions |
| Biochemical research | Laboratory synthesis and analytical reagent | Applied for introduction and removal of protecting groups |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperidine-4-carboxylic acid tert-butyl ester hydrochloride) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at 210 nm. |
| Related Substances | HPLC with UV detection | Separation and quantification of impurities (e.g., residual piperidine, di-tert-butyl dicarbonate, deprotected acid) relative to main peak using gradient elution. |
| Water Content | Karl Fischer titration | Electrochemical titration with iodine reagent where water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents (e.g., THF, DCM, MeOH) | Gas Chromatography (GC) with FID | Separation and quantification of volatile organic solvents using capillary column and flame ionization detection against external standards. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Content | Potentiometric titration with silver nitrate | Titration of chloride ions with AgNO3 solution using silver indicator electrode; endpoint detected by potential inflection. |
| Residue on Ignition | Gravimetric analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (700-800 C) and weighing. |
| Optical Rotation | [alpha]D measurement | Determination of specific rotation using sodium D-line light source in solution, indicating chiral purity and absence of racemization. |
| pH of 5% Aqueous Solution | pH meter measurement | Direct potentiometric measurement of hydrogen ion activity in a standardized aqueous suspension/solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as function of angle to determine volume-based particle size distribution. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and detection of specified pathogens following filtration, culture on selective media, and colony counting. |
| Appearance | Visual Inspection | Assessment of physical form, color, and clarity against established reference standards under controlled lighting conditions. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white to white crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 147°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.