4-AMINO-3-BROMO-5-NITROPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 89284-05-9 |
| Product name | 4-AMINO-3-BROMO-5-NITROPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-AMINO-3-BROMO-5-NITROPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-AMINO-3-BROMO-5-NITROPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-AMINO-3-BROMO-5-NITROPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antitumor agents (e.g., EGFR inhibitors) | Constructs pyridine ring substituents via multi-step reactions—including nitration, bromination, and aminolysis—for subsequent coupling to introduce arylamine or heterocyclic structures |
| Agrochemical Intermediates | Heterocyclic building block for preparing novel insecticides and fungicides | Serves as a nitrogen-containing heterocyclic synthon in Suzuki or Heck couplings to build bioactive triazine or pyrimidine derivatives |
| Materials Science | Synthetic precursor for organic optoelectronic materials (e.g., OLED emissive layer dopants) | Produces bromo-nitro-amino functionalized conjugated molecules via reduction, diazotization, and coupling reactions to tune HOMO/LUMO energy levels |
Manufacturing Quality Control of 4-AMINO-3-BROMO-5-NITROPYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, dehalogenated, reduction by-products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., DMF, acetone, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based reagent in anhydrous methanol medium. |
| Heavy Metals | ICP-OES | Measures total elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on anion-exchange column. |
| Sulfate Impurity | Ion Chromatography | Quantifies sulfate ions using suppressed conductivity detection after separation on anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established reference standard. |
| Bulk Density | ASTM D1895 | Measures mass per unit volume of freely settled powder using standardized graduated cylinder and balance. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of dry powder using Mie theory scattering analysis of laser beam passed through dispersed sample. |
Technical Specifications of 4-AMINO-3-BROMO-5-NITROPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-AMINO-3-BROMO-5-NITROPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-AMINO-3-BROMO-5-NITROPYRIDINE
Safety Information of 4-AMINO-3-BROMO-5-NITROPYRIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-AMINO-3-BROMO-5-NITROPYRIDINE
Industrial 4-AMINO-3-BROMO-5-NITROPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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