China Factory Direct
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| CAS number | 89402-43-7 |
| Product name | 5-Chloro-2,3-difluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of insecticide intermediates | Fluorochlorination, cyclization |
| Pharmaceuticals | Preparation of antiviral drug intermediates | Halogenation, coupling |
| Fine chemicals | Synthesis of specialty functional materials | Directed fluorination, substitution |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities in the sample under natural or standard lighting conditions. |
| Assay (Purity) | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase C18 column and a UV detector (typically around 254 nm) to determine the content of the main component via external standard method or area normalization method. |
| Gas Chromatography (GC) | Suitable for volatile samples; uses capillary column separation with FID detection for quantification, ideal for high-purity sample analysis. | |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyzes the chemical environments of hydrogen and fluorine atoms in the compound using ¹H-NMR and ¹⁹F-NMR to confirm molecular structure. |
| Mass Spectrometry (MS) | Determines the molecular ion peak (m/z) using ionization methods such as EI or ESI, verifying molecular weight and aiding structural identification. | |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Analyzes characteristic absorption peaks of functional groups (e.g., C-F, C-Cl, C=N), used for preliminary structural confirmation. | |
| Moisture Content | Karl Fischer Titration | Utilizes electrochemical titration principles to accurately measure water content in the sample; available in volumetric and coulometric methods. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents possibly remaining from manufacturing processes (e.g., methanol, ethanol, acetone, dichloromethane) according to ICH guidelines. |
| Related Substances (Impurities) | HPLC Method | Separates the main peak from impurity peaks using gradient elution, detecting and quantifying each impurity to assess sample purity and stability. |
| Melting Point | Melting Point Apparatus | Determines the initial and final melting temperatures using automated or manual melting point instruments, serving as a reference physical constant. |
| Chlorine Content | Elemental Analysis (CHNS/O) | Measures the content of carbon, hydrogen, nitrogen, sulfur/oxygen, and halogens to indirectly verify whether the chlorine content matches the theoretical value. |
| Fluorine Content | Ion Chromatography or Elemental Analysis | Total fluorine content can be determined by combustion coupled with ion chromatography, or quantitatively analyzed using an elemental analyzer. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measures residual levels of toxic metallic elements such as lead, cadmium, mercury, and arsenic to comply with pharmacopoeial or relevant safety standards. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.495–1.505 |
| Relative Density (20°C/25°C) | 1.38–1.42 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.