China Factory Direct
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| CAS number | 98167-06-7 |
| Product name | (R)-(+)-Indoline-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral building block for synthesizing protease inhibitors, antiviral agents, and neuroactive compounds | Prepared via asymmetric hydrogenation, enzymatic resolution, or chiral pool synthesis; employed as an intermediate in multistep organic synthesis |
| Chemical Research | Used to construct indoline-containing organic compound libraries for structure–activity relationship (SAR) studies | Employed as a chiral ligand or catalyst precursor in asymmetric catalysis, or converted into derivatives via acylation, alkylation, and other functionalization reactions |
| Agrochemical Development | Serves as a potential lead compound for designing novel insecticides or fungicides | Structurally modified and subjected to biological activity screening; functional groups are introduced via organic synthesis to optimize efficacy |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Enantioselective separation and quantification using a chiral stationary phase and UV detection at ~220 nm. |
| Chiral Purity (enantiomeric excess, ee) | Chiral HPLC or SFC | Separation of (R)- and (S)-enantiomers via chiral chromatography; ee calculated from peak area ratio. |
| Residual Solvents | GC-FID or GC-MS | Quantitative determination of volatile organic solvents (e.g., methanol, ethyl acetate) using headspace-GC with flame ionization or mass spectrometric detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification after acid digestion, based on elemental mass-to-charge ratio detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of non-volatile inorganic residue. |
| Optical Rotation | [α]D Measurement | Determination of specific rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral identity and enantiomeric integrity. |
| Related Substances (Impurities) | HPLC with UV Detection | Separation and quantification of structurally related impurities (e.g., (S)-enantiomer, decarboxylated or hydrolyzed by-products) using reversed-phase C18 column. |
| pH (of aqueous suspension) | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) to assess acidic character and potential degradation. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine D10, D50, D90 values for bulk handling and formulation suitability. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% |
| Optical Rotation | +110° to +115° (c=1, in methanol) |
| Melting Point | 148°C to 152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.