4-Chloro-6-iodoquinazoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 98556-31-1 |
| Product name | 4-Chloro-6-iodoquinazoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-6-iodoquinazoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-6-iodoquinazoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-6-iodoquinazoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs (e.g., quinazoline-based tyrosine kinase inhibitors) | Used in coupling and substitution reactions |
| Chemicals | Synthetic building block for pharmaceuticals | Applied in palladium-catalyzed coupling and nucleophilic substitution |
Manufacturing Quality Control of 4-Chloro-6-iodoquinazoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by separation on C18 column with gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Hg) via inductively coupled plasma mass spectrometry for high sensitivity. |
| Chlorine Content | Ion Chromatography | Determines chloride ion concentration after sample decomposition and anion separation with conductivity detection. |
| Iodine Content | Potentiometric Titration with AgNO3 | Quantifies iodide by titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change. |
| Water Content | Karl Fischer Titration | Measures water content volumetrically using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under controlled temperature and vacuum, indicating volatile and moisture content. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution by measuring angular variation in laser light scattering intensity. |
| Residue on Ignition | Gravimetric Ashing | Quantifies inorganic residue after high-temperature combustion in a muffle furnace, per USP <281>. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode. |
Technical Specifications of 4-Chloro-6-iodoquinazoline
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 218–222 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-6-iodoquinazoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-6-iodoquinazoline
Packaging of 4-Chloro-6-iodoquinazoline
Industrial 4-Chloro-6-iodoquinazoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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