China Factory Direct
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| CAS number | 98873-55-3 |
| Product name | 1H-Imidazol-1-ylacetonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as an intermediate in the synthesis of certain pharmaceuticals | Employed to construct target molecular structures via reaction with other compounds |
| Pesticides | Used as a precursor in the preparation of specific pesticide products | Chemically transformed to yield final biologically active products |
| Fine Chemicals | Used as a raw material for the production of other chemicals | Participates in various organic synthesis reactions, including addition and substitution |
| Research | Used as a reagent or starting material in laboratory research | Applied in organic synthesis experiments to develop novel compounds or optimize existing synthetic routes |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | A C18 column is used with water-acetonitrile or methanol-buffer as the mobile phase. A UV detector (210–254 nm) is employed for detection, and the content of the active ingredient is quantified using external standard or internal standard methods to evaluate product purity. |
| Impurity Profile Analysis | HPLC-UV / HPLC-MS | Gradient elution HPLC is used to separate impurities, combined with UV detection or mass spectrometry (LC-MS) for qualitative and quantitative analysis of degradation products, residual raw materials, by-products, etc., in compliance with ICH Q3B guidelines. |
| Moisture Content | Karl Fischer Titration Method | Iodine, sulfur dioxide, pyridine, and methanol are used in a Karl Fischer reagent that reacts quantitatively with water. The moisture content is determined by potentiometric or coulometric titration, suitable for trace moisture control in organic solvents (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | GC-FID/MS is performed using headspace or direct injection to detect residual organic solvents such as methanol, acetonitrile, DMF according to ICH Q3C standards, ensuring compliance with pharmaceutical or electronic-grade requirements. |
| Melting Point | Melting Point Apparatus Method | A digital melting point apparatus is used to determine the melting range (literature value approximately 58–62 °C), providing preliminary identification and batch consistency assessment. |
| Chloride / Inorganic Impurities | Ion Chromatography (IC) | The sample is dissolved in water or dilute acid and separated on an ion exchange column. An electrical conductivity detector is used to measure the concentration of inorganic anions such as Cl⁻ and SO₄²⁻ to ensure compliance with specified impurity limits. |
| pH Value (Aqueous Solution) | pH Meter Method | The sample is prepared as a specific concentration (e.g., 1% w/v) aqueous solution, and its pH is measured using a calibrated pH meter to assess acidity or alkalinity (usually neutral or slightly acidic). |
| Appearance and Color | Visual Inspection / Colorimetric Measurement | The solid form (white to off-white crystalline powder) and color are observed under natural light. A colorimeter (e.g., Lab*) may be used to quantify color changes, ensuring compliance with pharmacopoeia appearance requirements. |
| Content Uniformity (Batch-to-Batch) | HPLC Multi-Point Sampling Method | Samples from different parts of the same batch are analyzed for active ingredient content, and RSD (relative standard deviation) is calculated to ensure mixing uniformity (RSD ≤ 2.0%). |
| Thermal Stability (Decomposition Temperature) | Thermogravimetric Analysis (TGA) | Under nitrogen or air atmosphere, the sample is heated while monitoring weight change with temperature to determine the onset decomposition temperature, assessing thermal stability during storage and processing. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 62–66°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.