China Factory Direct
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| CAS number | 99-15-0 |
| Product name | Acetylleucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of amino acid–based drugs | Produced via N-acetylation of DL-leucine with acetic anhydride under basic conditions |
| Chemicals | Used as an organic synthesis intermediate | Employed as a starting material for peptide chain modification or introduction of protecting groups |
| Food | Precursor to nutritional fortificants (indirect use) | Hydrolyzed or enzymatically converted to L-leucine for use in nutritional supplement manufacturing |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Chemical Structure Confirmation | Infrared Spectroscopy (IR) | Confirm molecular functional groups and structural consistency by comparing characteristic absorption peaks with reference spectra. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR or ¹³C-NMR to analyze proton/carbon chemical shifts for precise verification of molecular structure. | |
| Mass Spectrometry (MS) | Determine molecular weight and structural fragments via molecular ion and fragment peaks; commonly coupled with chromatography (e.g., LC-MS). | |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase chromatography columns with UV detection (e.g., at 210 nm); quantify the main component by external standard or area normalization method. |
| Non-aqueous Titration | Titrate with perchloric acid in non-aqueous solvents; determine endpoint via potentiometry or indicator, then calculate content. | |
| Related Substances (Impurities) Check | HPLC with Gradient Elution | Optimize mobile phase gradient to separate and quantify individual impurity peaks; typically calculate using self-reference or corrected factor methods. |
| Optical Rotation | Polarimeter Measurement | Measure optical rotation of a sample solution under specified concentration and temperature to assess optical purity (since it is a DL-type, rotation should be close to 0°). |
| Drying Loss | Drying Method (105°C to Constant Weight) | Dry sample in an oven until constant weight is achieved; calculate percentage mass loss to evaluate moisture and volatile content. |
| Residue on Ignition | High-Temperature Ashing (600–800°C) | Ignite sample at high temperature and weigh residual inorganic matter to control inorganic salts or metal impurities. |
| Heavy Metals | Thioacetamide Method (Chinese Pharmacopoeia) | React under weakly acidic conditions with thioacetamide to produce color; compare with standard lead solution to control total heavy metal content. |
| pH Value | pH Meter Measurement | Prepare a solution of defined concentration and directly measure pH to ensure compliance with process or formulation requirements. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Use headspace or direct injection to separate and quantify organic solvent residues (e.g., methanol, ethanol, ethyl acetate, etc.). |
| Water Content | Karl Fischer Titration (Volumetric Method) | Utilize the quantitative reaction between iodine, sulfur dioxide, and water in a pyridine/methanol system to precisely determine trace water content. |
| Test Item | Specification |
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| Appearance | White to almost white powder to crystal |
| Assay | 97.5~102.5% |
| Loss on drying | ≤0.5% |
| Chloride | ≤0.02% |
| Ammonium | ≤0.02% |
| Sulfate | ≤0.02% |
| Fe | ≤10 ppm |
| Heavy metal as Pb | ≤20 ppm |
| As | ≤2 ppm |
| Residue on ignition | ≤0.30% |
| pH | 1.7-3.0 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.