China Factory Direct
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| CAS number | 99-28-5 |
| Product name | 99-28-5 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Bromination and nitration |
| Pharmaceuticals | Intermediate for antimicrobial drug synthesis | Nitration, bromination, and subsequent substitution reactions |
| Dyes | Raw material for specialty dye synthesis | Coupling reaction following bromination and nitration |
| Chemical research | Laboratory reagent | Synthesis of specific organic compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~280 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV | Separation and quantification of structurally related impurities (e.g., mono-brominated isomers, nitrophenol, dibromoanisole) using gradient HPLC-UV. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration measuring water content via iodine-sulfur dioxide reaction in anhydrous methanol-based solvent. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of residual non-volatile matter. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of heavy metals (Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (ASTM D1565). |
| Organic Volatile Impurities (e.g., dichloromethane, toluene) | GC-FID | Headspace or direct injection GC with flame ionization detection for residual solvents per ICH Q3C guidelines. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of crystalline form and color intensity against standardized platinum-cobalt (APHA) scale in solution. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities (e.g., residual phenol, HBr) with standardized NaOH using phenolphthalein indicator. |
| Bromine Content | Oxygen Flask Combustion + Potentiometric Titration | Quantitative release of bromide via combustion, followed by titration with AgNO₃ using potentiometric endpoint detection. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dispersed phase using Mie scattering theory and optical diffraction patterns. |
| Bulk Density | USP <616> Method I | Determination of mass per unit volume for freely settled powder in a calibrated cylinder. |
| Microbial Limits | Membrane Filtration / Plate Count | Enumeration of aerobic microorganisms following pharmacopeial filtration and culture on TSA/R2A agar (if applicable for non-sterile intermediates). |
| Test Item | Specification |
|---|---|
| Appearance | White to orange crystalline powder |
| Purity | >=98.0% (GC) |
| Melting Point | 112-116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.