China Factory Direct
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| CAS number | 99-31-0 |
| Product name | 5-Aminoisophthalic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor agents (e.g., gemcitabine derivatives) and antimicrobial compounds | Produced via diazotization-hydrolysis or catalytic hydrogenation reduction of 5-nitroisophthalic acid; subsequently employed in multi-step reactions—including amidation and cyclization—to construct active molecular frameworks |
| Dyes | Key monomer for manufacturing high-performance azo dyes and reactive dyes, used in dyeing polyester and cellulosic fibers | Coupled with diazonium salts to form azo structures; or subjected to chlorosulfonation followed by condensation with cyanuric chloride to introduce reactive groups, yielding reactive dye intermediates |
| High-performance polymers | Comonomer for synthesizing heat-resistant polyamides, polyesters, and liquid crystalline polymers | Undergoes melt polycondensation with diamines or diols under nitrogen atmosphere at 280–320 °C, incorporating rigid meta-aminobenzoic acid structural units to enhance thermal stability |
| Pesticides | Structural building block for synthesizing novel herbicides and plant growth regulators | After diazotization, coupled with phenolic compounds or reacted with aldehydes via Mannich reaction to construct biologically active side chains containing amino-substituted aryl rings |
| Test Item | Common Testing Method | Method Overview |
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| Appearance | Visual Inspection | Observe the color and physical state of the sample under natural or standard lighting to determine if it is white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) | Perform infrared scanning of the sample and reference standard under identical conditions; compare characteristic absorption peaks (e.g., functional groups such as —NH₂, —COOH). |
| Proton Nuclear Magnetic Resonance (¹H-NMR) | Dissolve the sample in a deuterated solvent and record the ¹H-NMR spectrum; confirm structural consistency through chemical shifts, peak shapes, and integration areas. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically around 254 nm); quantify the main component using external or internal standard methods. |
| Titration (Acid-Base Titration) | Titrate the carboxyl group's acidity using a standardized NaOH solution, with phenolphthalein or potentiometric detection for endpoint determination; calculate active ingredient content. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient or isocratic elution; calculate individual impurity levels using reference standards or the area normalization method. |
| Water Content | Karl Fischer Titration | Determine water content using coulometric or volumetric Karl Fischer methods, suitable for trace moisture analysis. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and calculate the percentage weight loss, indicating volatile impurities or residual solvents. |
| Residue on Ignition (Sulphated Ash) | Sulphated Ash Method | Ignite the sample at high temperature, treat with sulfuric acid, then weigh the residue to assess inorganic impurity content. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure concentrations of heavy metal elements such as lead, cadmium, mercury, and arsenic; ensure compliance with pharmacopoeial or customer-specified limits. |
| Solubility | Solubility Test | Test solubility in various solvents such as water, ethanol, acetone, and DMSO; used for process development and formulation guidance. |
| Particle Size Distribution | Laser Diffraction Analysis (LDA) | Disperse the sample using wet or dry methods to measure particle size parameters such as D10, D50, and D90, ensuring consistent physical properties across batches. |
| Crystal Form | X-Ray Powder Diffraction (XRD) | Analyze characteristic diffraction peaks to identify crystal structure and detect polymorphic forms, ensuring batch-to-batch consistency in crystallinity. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 235-240 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.