China Factory Direct
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| CAS number | 99-50-3 |
| Product name | Protocatechuic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antioxidant; intermediate for anti-inflammatory drugs | Used as a precursor in the synthesis of bioactive compounds for cardiovascular drug and neuroprotective agent development |
| Cosmetics | Skin-lightening agent; antioxidant additive | Incorporated into skincare formulations to inhibit tyrosinase activity and reduce melanin production |
| Food | Natural preservative; antioxidant ingredient | Applied in food preservation to retard oxidative spoilage and extend shelf life |
| Agriculture | Plant growth regulator; antimicrobial agent | Formulated into botanical pesticides to suppress pathogenic microbial growth and enhance crop stress tolerance |
| Chemical Research | Organic synthesis intermediate; analytical reagent | Employed in laboratory-scale synthesis of polyphenolic compounds and involved in coupling, esterification, and related reactions |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with methanol-water or acetonitrile-water containing acidic additives (e.g., phosphoric acid, formic acid) as the mobile phase. Detection is performed at around 260 nm using a UV detector. The content of protocatechuic acid is quantified by external or internal standard methods. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Same as above; purity is assessed by peak area normalization to evaluate the main component peak, checking for impurity peaks to determine sample purity. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Protocatechuic acid shows characteristic absorption peaks near 210 nm and 260 nm. Preliminary identification is achieved by comparing the UV spectrum with that of a reference standard. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Used to identify functional groups. Protocatechuic acid exhibits characteristic absorption peaks at approximately 3400 cm⁻¹ (hydroxyl group), 1680 cm⁻¹ (carboxyl C=O stretch), and 1600 cm⁻¹ (aromatic ring). | |
| Impurity Testing | High-Performance Liquid Chromatography (HPLC) | HPLC is used to detect possible impurities such as synthesis intermediates, degradation products, or related substances. Identification is based on retention time, and quantification is performed using peak area. |
| Residual Solvents | Gas Chromatography (GC) | Suitable for detecting residual organic solvents (e.g., methanol, ethanol, acetone) from the manufacturing process, analyzed using a capillary column and FID detector. |
| Moisture Content | Karl Fischer Titration | Accurately determines moisture content in samples, available in volumetric or coulometric methods, commonly used in quality control of raw materials or final products. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detects heavy metal residues such as lead, cadmium, arsenic, and mercury to ensure compliance with pharmacopeial or food safety limits. |
| Melting Point | Melting Point Determination | The melting point of protocatechuic acid (literature value approximately 196–198°C) is measured using a melting point apparatus for preliminary identification and purity assessment. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 198–202°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.