2-Chloro-4-nitrobenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 99-60-5 |
| Product name | 2-Chloro-4-nitrobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-nitrobenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-nitrobenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-nitrobenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the production of the diuretic ethacrynic acid | Synthesized into ethacrynic acid via esterification, reduction, and substitution reactions starting from 2-chloro-4-nitrobenzoic acid |
| Pharmaceutical Industry | Intermediate in the synthesis of the antiarrhythmic drug aprindine | Serves as a benzoic acid derivative scaffold in multistep chemical syntheses to construct the active pharmaceutical ingredient |
| Dye Industry | Intermediate for neutral dyes and azo dyes | Reduced to generate the dye intermediate 2-chloro-4-aminobenzoic acid, followed by diazotization and coupling |
| Agrochemical Industry | Intermediate in the production of herbicides and plant growth regulators | Participates in amine addition, condensation, and other organic synthesis unit operations to prepare nitro- or amino-containing agrochemicals |
| Organic Synthesis | Analytical reagent for alcohols and phenols | Used in chemical analysis as a selective functional group detection or derivatization reagent |
Manufacturing Quality Control of 2-Chloro-4-nitrobenzoic acid
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically appears as a pale yellow to yellow crystalline powder. |
| Melting Point | Capillary Melting Point Determination | Determine the temperature at which the substance transitions from solid to liquid using a melting point apparatus; used to assess purity and compound identity. Standard melting point is approximately 185–188°C. |
| Assay (Active Ingredient) | High-Performance Liquid Chromatography (HPLC) | Quantify the main component using a reversed-phase C18 column and UV detector (e.g., 254 nm), based on retention time and peak area. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Detect potential residual intermediates or by-products from synthesis (e.g., unreacted starting materials, isomers) to evaluate purity. |
| Moisture Content | Karl Fischer Titration | Accurately measure water content in the sample; suitable for trace water analysis to ensure product stability. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Method | Dry the sample at a specified temperature (e.g., 105°C), then calculate the content of volatile substances based on weight difference before and after drying. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, ethyl acetate) from manufacturing processes, ensuring compliance with pharmacopoeial requirements. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Measure the levels of heavy metal elements such as lead, arsenic, and cadmium to ensure compliance with safety limits (e.g., Chinese Pharmacopoeia or ICH guidelines). |
| Chlorides | Ion Chromatography or Argentometric Method | Detect inorganic chloride ion impurities to assess the completeness of post-processing purification. |
| Nitro Group Content (Supportive) | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilize characteristic absorption of nitro groups at specific wavelengths (~265 nm and 350 nm) to indirectly assess structural integrity. |
Technical Specifications of 2-Chloro-4-nitrobenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White to orange crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-nitrobenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-nitrobenzoic acid
Packaging of 2-Chloro-4-nitrobenzoic acid
Industrial 2-Chloro-4-nitrobenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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