China Factory Direct
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| CAS number | 99-66-1 |
| Product name | 2-Propylpentanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Raw material for antiepileptic drugs | Used as the active pharmaceutical ingredient in the synthesis of antiepileptic agents such as sodium valproate and magnesium valproate, via esterification, neutralization, and other chemical reactions |
| Pharmaceuticals | Treatment of bipolar disorder | Formulated directly into extended-release tablets or capsules for mood stabilization and modulation of central nervous system function |
| Chemical Research | Organic synthesis intermediate | Employed in laboratory-scale synthesis as a precursor for other organic compounds, participating in acylation, condensation, and related reactions |
| Pharmaceuticals | Prophylactic treatment of migraine | Formulated into oral dosage forms for migraine prophylaxis, with mechanism of action involving modulation of the GABAergic system |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and UV detector (typically at 210–220 nm), with methanol-buffer solution (e.g., phosphate buffer) as the mobile phase for quantitative analysis of valproic acid, offering high sensitivity and good reproducibility. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separates organic impurities in valproic acid (such as synthesis intermediates and degradation products) using gradient or isocratic elution. Qualitative and quantitative analysis is performed by comparison with reference standards to assess purity. |
| Residual Solvents | Gas Chromatography (GC) | Employs a capillary column (e.g., DB-624 or similar polarity column) and FID detector to determine residual organic solvents (e.g., methanol, ethanol, acetone) from manufacturing processes, ensuring compliance with pharmacopoeial limits for residual solvents. |
| Water Content | Karl Fischer Titration | Determines water content precisely based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment; suitable for moisture-sensitive compounds like valproic acid. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Used to identify different crystalline forms of valproic acid, ensuring consistency in crystal structure across batches and guaranteeing stability and dissolution performance. |
| Infrared Identification | Infrared Spectroscopy (IR) | Confirms chemical structure by comparing sample spectra with standard reference spectra, using characteristic absorption peaks (e.g., carboxyl stretching vibration around 1710 cm⁻¹); used for identification of raw material authenticity. |
| Melting Point | Melting Point Determination | Determined using a melting point apparatus. The melting temperature of valproic acid is approximately −20°C to −18°C (literature values); in practice, it is often measured as a derivative or salt form, used for preliminary identification and purity assessment. |
| Solution Clarity and Color | UV-Visible Spectrophotometry / Visual Inspection | The sample is prepared as a solution and examined visually for clarity and color. Absorbance may be measured at specific wavelengths (e.g., 400–500 nm) when necessary to control appearance quality. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determines levels of heavy metal elements such as lead, cadmium, and mercury to ensure compliance with safety limits for pharmaceutical raw materials. |
| Microbial Limits | Microbial Limits Testing | Performs tests according to requirements of the Chinese Pharmacopoeia or other relevant pharmacopoeias, including total aerobic microbial count, total mold and yeast count, and specified pathogens (e.g., Escherichia coli), to ensure microbiological safety. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | -70 to -65°C |
| Refractive Index (n20/D) | 1.405 to 1.410 |
| Relative Density (20°C/25°C) | 0.975 to 0.985 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.