China Factory Direct
|
|
| CAS number | 99-90-1 |
| Product name | 4'-Bromoacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antihistamines, antidepressants, and other pharmaceuticals | Used as an aryl ketone building block in reduction, condensation, or nucleophilic substitution reactions |
| Agrochemicals | Intermediate in the synthesis of insecticides and herbicides | Applied in coupling or substitution reactions via the bromine atom to construct bioactive molecular frameworks |
| Dyes | Used in the synthesis of specific-structure organic dyes and pigments | Applied in Friedel–Crafts acylation or subsequent functional group transformations |
| Fragrances | Used to synthesize fragrance compounds with specific olfactory profiles | Processed via reduction or condensation to yield aromatic alcohols or enone-based fragrance compounds |
| Materials Science | Precursor for liquid crystal monomers or functional polymeric materials | Applied in polymerization or structural modification via the phenyl ring and carbonyl group to tailor material properties |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | Gas Chromatography (GC) | Using a gas chromatograph equipped with a flame ionization detector (FID) and reference standards for quantification, this method effectively separates p-bromoacetophenone from its impurities, suitable for purity testing and content analysis. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Employs a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and a UV detector at 254 nm or 260 nm. Offers high sensitivity and is ideal for accurate quantification of target compounds in complex matrices. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed molecular structural information, confirming characteristic signals of p-bromoacetophenone (e.g., aromatic protons, carbonyl carbon, bromine substitution position), serving as the gold standard for structural verification. |
| Molecular Weight Identification | Mass Spectrometry (MS) | Utilizes electron ionization (EI) or electrospray ionization (ESI) mass spectrometry to detect the molecular ion peak (M⁺), enabling accurate determination of molecular weight and supporting structural analysis and impurity identification. |
| Impurity Analysis | GC-MS or HPLC-MS | Combines chromatographic separation with mass spectrometric detection to identify unknown impurities and perform qualitative analysis; commonly used for detecting residual solvents or by-products in synthetic processes. |
| Residual Solvent Testing | Gas Chromatography (GC-FID/MS) | In accordance with pharmacopeial guidelines (e.g., ICH Q3A/Q3C), detects organic solvents possibly remaining from synthesis (such as acetone, ethanol, dichloromethane, etc.) to ensure compliance with safety limits. |
| Melting Point Determination | Micro Melting Point Apparatus | Determines the melting temperature range of the sample, providing an initial assessment of purity and identity of p-bromoacetophenone, serving as a preliminary quality check. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Verifies the presence of functional groups through characteristic absorption peaks (e.g., C=O stretching vibration around 1670–1690 cm⁻¹, C–Br bond absorption around 550–650 cm⁻¹), aiding in structural confirmation. |
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow or light orange powder to lump |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 57.0–59.0°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.