China Factory Direct
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| CAS number | 99-93-4 |
| Product name | 4'-Hydroxyacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates (e.g., synthesis of β-blockers) | Chemical synthesis, catalytic reactions |
| Cosmetics | Antioxidant and preservative (replacing conventional preservatives) | Extraction, purification, formulation addition |
| Fine Fragrances | Fragrance fixative and component in perfume compounding | Esterification, blending |
| Organic Synthesis | Synthesis of other fine chemicals (e.g., dyes, polymer monomers) | Catalytic oxidation, functional group transformation |
| Agrochemicals | Agrochemical intermediates (e.g., synthesis of herbicides or fungicides) | Condensation reactions, post-reaction purification |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state of the sample under natural or standard lighting to determine if it is a white to off-white crystalline powder, checking for impurities or discoloration. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 245–280 nm wavelength), employing methanol-water or acetonitrile-water as the mobile phase. Quantify the main component using external or internal standard methods; purity is typically required to be ≥99.0%. |
| Melting Point | Melting Point Determination (Capillary Method) | Determine the melting temperature using a melting point apparatus or capillary method. The melting point of p-Hydroxyacetophenone is typically 109–112°C, used to assess purity and identity. |
| Moisture Content | Karl Fischer Titration | Use Karl Fischer reagent to titrate water content in the sample; suitable for trace moisture analysis. Moisture content is generally controlled to ≤0.5%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Detect potential impurities such as synthesis intermediates, by-products, or degradation products (e.g., phenolic compounds, acetylation by-products) using HPLC. Typically, individual impurity ≤0.1% and total impurities ≤0.5%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Colorimetric Method | After sample digestion, determine residual heavy metals such as lead, cadmium, and mercury using atomic absorption spectroscopy. Limits generally comply with pharmacopoeial requirements (e.g., ≤20 ppm). |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, acetone, toluene) using headspace GC with FID detection, in compliance with ICH Q3C guidelines. |
| Sulfated Ash / Residue on Ignition | Residue on Ignition Test | Weigh the residue after high-temperature ignition of the sample to evaluate inorganic impurity content. Typically required to be ≤0.1%. |
| pH Value (Solution) | pH Meter Method | Measure the pH of a defined concentration aqueous solution of p-Hydroxyacetophenone (e.g., 1% w/v) using a pH meter to assess acidity or alkalinity. Generally weakly acidic with pH around 5.0–7.0. |
| Infrared Identification (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Record infrared spectrum using KBr pellet or ATR method and compare with reference spectrum to confirm consistency of characteristic molecular absorption peaks. |
| Test Item | Specification |
|---|---|
| Appearance | White to Almost white powder to crystal |
| Purity | |
| MCB | |
| Phenol | |
| 2-HAP | |
| 4-CAP | |
| Water | |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.