4-Hydroxybenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 99-96-7 |
| Product name | 4-Hydroxybenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Hydroxybenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Hydroxybenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Hydroxybenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate for parabens (e.g., methyl, ethyl, and propyl parabens) and anti-inflammatory drugs | Esterification, acylation, catalytic hydrogenation |
| Food | Used as a preservative (e.g., methyl, ethyl, and propyl parabens) to inhibit molds and yeasts | Esterification, followed by purification and incorporation into food products |
| Cosmetics | Used as a preservative to prevent microbial contamination and extend product shelf life | Esterification to produce parabens, formulated into emulsions and creams |
| Pesticides | Used as a synthetic intermediate for certain fungicides and plant growth regulators | Condensation, substitution reactions |
| Dyes | Used as a synthetic intermediate for azo dyes and disperse dyes | Diazotization–coupling reaction |
| High-performance polymers | Used in the synthesis of liquid crystal polymers and aromatic polyesters | Polycondensation, transesterification |
Manufacturing Quality Control of 4-Hydroxybenzoic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a C18 column with methanol-water (or buffer) as the mobile phase and UV detector (254 nm). Quantification is performed using external standard or internal standard method. This method offers high accuracy and strong specificity, and is recommended by pharmacopoeia. |
| Content Determination | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measures absorbance at 254 nm; content is calculated based on a standard curve. Simple to operate but susceptible to interference from impurities, suitable for rapid preliminary screening. |
| Melting Point Determination | Melting Point Apparatus Method | As per Chinese Pharmacopoeia, determines the melting range of p-hydroxybenzoic acid (approximately 213–217°C), used for initial identification and purity assessment. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Uses gradient or isocratic elution to detect potential impurities such as benzoic acid, o-hydroxybenzoic acid, and m-hydroxybenzoic acid. Impurity limits are controlled using either the main component self-control method or external standard method. |
| Moisture Content Determination | Karl Fischer Titration | Quantitatively measures trace moisture through reaction between iodine-sulfur dioxide-pyridine-methanol system and water. Suitable for moisture control in active pharmaceutical ingredients. |
| Inorganic Impurities (e.g., Chloride, Sulfate) | Turbidimetry / Ion Chromatography | Chloride tested by silver nitrate turbidimetry; sulfate by barium chloride turbidimetry. Ion chromatography enables simultaneous detection of multiple anions with high sensitivity, suitable for high-purity products. |
| Heavy Metal Testing | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, lead, cadmium, mercury, and other heavy metals are determined by AAS or Inductively Coupled Plasma Mass Spectrometry (ICP-MS), meeting pharmacopoeial limits. |
| Identification Test | Infrared Spectroscopy (IR) | Compare infrared spectrum with that of reference p-hydroxybenzoic acid. Characteristic absorption peaks include: 3200–3500 cm⁻¹ (phenolic OH), 1680 cm⁻¹ (carboxyl C=O), and 1600/1580 cm⁻¹ (benzene ring). |
| Identification Test | Thin Layer Chromatography (TLC) | Uses silica gel G plates; developing solvent such as ethyl acetate-methanol-water (8:1:1). Visualized with ferric chloride reagent or under UV light. Identification confirmed by comparing Rf values with reference standard. |
| Solubility Determination | Shake Flask Method / Solubility Apparatus Method | Determines solubility in water, ethanol, ether, etc., at 25°C. Used to evaluate suitability for formulation processes, within pharmacopoeial specifications. |
| pH Value Determination | pH Meter Method | Prepare a solution of specified concentration (e.g., 1%), measure pH using calibrated pH meter. Typically ranges from 4.5 to 5.5, reflecting acidity strength and purity. |
Technical Specifications of 4-Hydroxybenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Melting Point | 185–187°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Hydroxybenzoic acid
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NMR Spectra of 4-Hydroxybenzoic acid
Packaging of 4-Hydroxybenzoic acid
Industrial 4-Hydroxybenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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