6-Fluorochromane-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 99199-60-7 |
| Product name | 6-Fluorochromane-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 6-Fluorochromane-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Fluorochromane-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Fluorochromane-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing antidiabetic drugs | Used as a key chiral intermediate in the synthesis of DPP-4 inhibitors, such as in constructing the core structure of saxagliptin |
| Organic Synthesis | Building block for fluorinated heterocyclic compounds | Participates in coupling, esterification, or reduction reactions via its carboxylic acid functional group for multistep synthesis of complex molecules |
| Fine Chemicals | Raw material for high-value fluorinated chemical products | Applied in the preparation of fluorinated functional materials or biologically active molecules, compatible with asymmetric synthesis and catalytic transformation processes |
Manufacturing Quality Control of 6-Fluorochromane-2-carboxylic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible foreign matter of the sample under natural light or standard light source. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with water-organic solvent (e.g., methanol or acetonitrile) containing ion-pair reagent or buffer salt as mobile phase. Detect using a UV detector (usually at 254 nm or 220 nm), and calculate the purity of the main peak by external standard method or area normalization method. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze hydrogen and carbon spectra using ¹H-NMR and ¹³C-NMR to confirm that the molecular structure matches the target compound; ¹⁹F-NMR can be used to confirm the position of fluorine atoms if present. |
| Structure Confirmation | Mass Spectrometry (MS, e.g., LC-MS or ESI-MS) | Determine the molecular ion peak ([M+H]⁺ or [M-H]⁻) to verify whether the molecular weight is consistent with the theoretical value, assisting in structural confirmation. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, detect residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) using capillary columns, typically employing headspace injection. |
| Moisture Content | Karl Fischer Titration | Determine moisture content using coulometric or volumetric methods, suitable for trace moisture detection, ensuring the raw material meets drying requirements. |
| Melting Point | Capillary Melting Point Determination | Measure the initial and final melting temperatures using a melting point apparatus, used for identification and assessing purity (impurities lower and broaden the melting range). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to purity testing but with gradient elution to enhance separation capability. Detect and quantify each related substance (e.g., synthetic intermediates, degradation products). Usually set limits for individual impurities and total impurities. |
| Chiral Purity (If Applicable) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to detect enantiomer impurities and evaluate optical purity, which is crucial when stereocenters are involved. |
| Ash/Residue on Ignition | Residue on Ignition Test | Igonize the sample to constant weight at high temperature and determine the amount of non-volatile inorganic impurities to reflect the level of inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect the residual levels of toxic heavy metals such as lead, cadmium, mercury, and arsenic to meet pharmacopoeia or international standards (e.g., ICH Q3D). |
Technical Specifications of 6-Fluorochromane-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow solid |
| Purity | ≥98.0% |
| Water | ≤1.0% |
| Single impurity | ≤1.0% |
| Total impurities | ≤2.0% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 6-Fluorochromane-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Fluorochromane-2-carboxylic acid
Safety Information of 6-Fluorochromane-2-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 6-Fluorochromane-2-carboxylic acid
Industrial 6-Fluorochromane-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply