China Factory Direct
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| CAS number | 99275-47-5 |
| Product name | 1-BOC-5-METHOXYINDOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key pharmaceutical intermediate | Used to synthesize 5-methoxyindole-3-acetic acid and its derivatives as building blocks for 5-HT receptor antagonists or agonists. |
| Pharmaceutical Industry | Drug discovery and development | Applied in the synthesis of indole-containing active pharmaceutical ingredients (APIs), such as anti-inflammatory or antitumor agents, leveraging the controlled deprotection of the N-BOC group. |
| Organic Synthesis | Synthetic building block | Deprotected under acidic conditions to generate the 5-methoxyindole intermediate for subsequent electrophilic substitution reactions (e.g., Vilsmeier-Haack formylation). |
| Scientific Research | Laboratory reagent | Employed in structural modification studies of indole compounds, particularly for nitrogen protection and regioselective reactions at the indole nitrogen atom. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents based on flame ionization response after gas chromatographic separation. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants via mass spectrometric detection of elemental ions. |
| Chloride Content | Ion Chromatography | Separates and detects chloride ions using suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using capillary tube observation. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral compound in solution using plane-polarized light. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in laser light scattering. |
| pH of Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in aqueous suspension using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.