China Factory Direct
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| CAS number | 99306-64-6 |
| Product name | NALPHA-(TERT-BUTOXYCARBONYL)-L-ARGININE 4-NITROANILIDE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing peptide-based drugs, used to incorporate arginine residues into peptide chains | Used as a Boc-protected arginine derivative in solid-phase peptide synthesis (SPPS) to form amide bonds |
| Biochemical Research | Chromogenic substrate for measuring protease activity (e.g., trypsin) | Enzymatic hydrolysis releases 4-nitroaniline, yielding a measurable absorbance change at 405 nm |
| Peptide Synthesis | Provides side-chain-protected L-arginine units to suppress side reactions | Employed in Fmoc/Boc orthogonal protection schemes; the Boc group is removed under acidic conditions |
| Analytical Chemistry | Reference standard or calibration material for HPLC or mass spectrometry analysis | Dissolved in an appropriate solvent (e.g., DMSO/water mixture) prior to injection |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-254 nm, comparing peak area to certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by HPLC separation and UV response relative to main peak. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, methanol) via gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual solids. |
| Heavy Metals | ICP-OES | Quantifies toxic metals (Pb, Cd, Hg, As, Ni) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Determines chloride ions using silver nitrate titrant and silver electrode endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution based on light scattering pattern. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
| Appearance | Visual Inspection | Assesses physical form, color, and homogeneity against established reference standard under controlled lighting. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | -20.0° to -24.0° (c=1, 6M HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.