China Factory Direct
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| CAS number | 99349-68-5 |
| Product name | (M-ACRYLAMIDOPHENYL)BORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Targeted drug carriers; glycoprotein recognition probes | Enables reversible covalent binding between boronic acid groups and carbohydrate structures in antibody–drug conjugates (ADCs), facilitating tumor cell-specific recognition and drug delivery |
| Biological Analysis | Fluorescent sensing and biomolecule detection | Functions as a boronic acid-functionalized fluorescent probe; specific binding to vicinal diol motifs (e.g., glucose, ribose in RNA) induces measurable fluorescence signal changes for in vitro diagnostics and cellular imaging |
| Materials Science | Construction of smart hydrogels and responsive polymers | Acts as a functional monomer in free-radical copolymerization to produce hydrogels responsive to both pH and sugar concentration, suitable for controlled drug release systems |
| Organic Synthesis | Boronic acid-based functional intermediates | Used in Suzuki–Miyaura cross-coupling reactions to introduce acrylamide groups, enabling subsequent grafting of polymer chains or biomolecules |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by comparing retention times and peak areas relative to the main peak using a validated gradient method. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, THF, ethyl acetate) via headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| pH (1% w/v aqueous suspension) | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode and buffer standards. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry powder mode using Mie scattering theory and standardized dispersion protocol. |
| Bulk Density | USP <616> Tap Density Test | Determines mass per unit volume after mechanical tapping in a graduated cylinder per United States Pharmacopeia guidelines. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.