China Factory Direct
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| CAS number | 99365-48-7 |
| Product name | 4-BROMOOXINDOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of antitumor drug intermediates | Used as a starting material for synthesizing indole derivatives |
| Agrochemical Industry | Intermediate for insecticides or fungicides | Applied in the construction of heterocyclic compounds |
| Materials Science | Synthesis of functional materials | Involved in polymerization reactions or molecular structure modification |
| Organic Synthesis | Synthesis of other nitrogen-containing heterocyclic compounds | Transformed via substitution, condensation, and related reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 4-bromoindolin-2-one by reversed-phase HPLC with UV detection at ~280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separates and quantifies structurally related impurities (e.g., unreacted indolinone, bromination by-products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., DMF, toluene, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pd, Ni, Fe) via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration | Determines water content electrochemically by iodine titration in anhydrous methanol/pyridine medium, based on stoichiometric reaction with water. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid-to-liquid phase transition occurs, indicating purity and identity via comparison to literature value (~142–144 °C). |
| Residue on Ignition | Gravimetric Analysis | Quantifies inorganic ash residue after high-temperature incineration (700–800 °C) and weighing of the cooled crucible. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity (though compound is achiral, detects potential chiral contaminants or degradation). |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension via analysis of laser light scattering pattern. |
| pH of Aqueous Suspension | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) to detect acidic/basic degradation products or residual reagents. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Quantifies volatile content (moisture, solvents) by measuring mass loss upon controlled heating (e.g., 105 °C, 2 h) under nitrogen. |
| Microbial Limits | Membrane Filtration & Culture | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods (USP <61>, <62>). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.