China Factory Direct
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| CAS number | 99494-01-6 |
| Product name | N-Methyl-D-prolinol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral auxiliary in asymmetric synthesis reactions | Asymmetric catalytic synthesis |
| Pharmaceuticals | Preparation of certain pharmaceutical intermediates | Organic synthesis |
| Chemicals | Preparation of surfactants | Esterification |
| Chemicals | Used as a solvent or stabilizer | Dissolution and blending |
| Research | Key reagent for chiral recognition studies | Development of analytical testing methods |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies N-methyl-D-prolinol content by retention time and peak area comparison against a certified reference standard. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine consumption in a pyridine-methanol solvent system. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Identifies and quantifies volatile organic solvents (e.g., methanol, THF) using headspace equilibration and GC separation. |
| Optical Rotation | [a]D Measurement using Polarimetry | Determines specific optical rotation at 20 C and 589 nm to confirm chiral integrity and enantiomeric identity. |
| Acid Value | Acid-Base Titration with NaOH | Measures free acid impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Heavy Metals | ICP-OES | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) after acid digestion by measuring element-specific atomic emission intensities. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of liquid sample against standard specifications under controlled lighting. |
| Density | Digital Density Meter | Determines mass per unit volume at specified temperature (e.g., 20 C) using oscillating U-tube principle. |
| Refractive Index | Refractometry | Measures bending of light through the sample at 20 C to assess purity and consistency. |
| Related Substances | HPLC with UV Detection | Separates and quantifies structurally related impurities (e.g., N-methylproline, D-prolinol) using reversed-phase chromatography and UV absorbance. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -15.0 to -19.0 deg (c=1, in CHCl3) |
| Refractive Index (n20/D) | 1.475 to 1.485 |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Odor | Characteristic mild amine-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.