3-N-Boc-aminopyrrolidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 99724-19-3 |
| Product name | 3-N-Boc-aminopyrrolidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-N-Boc-aminopyrrolidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-N-Boc-aminopyrrolidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-N-Boc-aminopyrrolidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Organic synthesis intermediate for preparing drug molecules, particularly bioactive compounds containing a pyrrolidine moiety | Serves as a building block in multistep synthesis; undergoes selective reactions using Boc protecting groups, followed by deprotection to yield the target amine |
| Research | Starting material for chemical and biological research, including development of new pharmaceuticals or bioprobes | Used in laboratory-scale organic synthesis, commonly applied in solid-phase synthesis or combinatorial chemistry |
| Biotechnology | Potentially employed in preparing peptide analogs or enzyme inhibitors to modify biomacromolecular structures | Introduces the pyrrolidinyl group via liquid-phase or solid-phase synthesis to optimize pharmacokinetic properties |
Manufacturing Quality Control of 3-N-Boc-aminopyrrolidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., THF, DMF, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity. |
| Residual Metals (e.g., Pd, Ni, Fe) | ICP-MS | Quantification of trace metal catalysts and contaminants by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution following sample dissolution and dilution. |
| Residual Boc Reagent (Di-tert-butyl dicarbonate) | GC-FID | Direct GC-FID analysis to detect and quantify unreacted Boc anhydride based on retention time and calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-state phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| pH (1% w/v aqueous suspension) | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Loss on Drying | Gravimetric Analysis | Weight loss determination after drying under specified vacuum/temperature conditions to assess volatile content and moisture. |
Technical Specifications of 3-N-Boc-aminopyrrolidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 58-62°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -19.0° (c=1, in CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-N-Boc-aminopyrrolidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-N-Boc-aminopyrrolidine
Packaging of 3-N-Boc-aminopyrrolidine
Industrial 3-N-Boc-aminopyrrolidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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