China Factory Direct
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| CAS number | 99725-12-9 |
| Product name | 2-Fluoro-5-bromobenzyl bromide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for preparing fluorinated and brominated drug molecules, including anticancer, antiviral, and central nervous system-active compounds | Introduced into target molecular scaffolds via nucleophilic substitution, Suzuki coupling, Heck reaction, and other organic synthesis methods |
| Agrochemicals | Intermediate for synthesizing biologically active fluorinated aryl derivatives used in novel insecticides or herbicides | Active agrochemical structures constructed through Grignard reagent reactions, metal-catalyzed cross-coupling, and related steps |
| Materials Science | Building block for synthesizing fluorinated functional materials, such as liquid crystals, organic optoelectronic materials, and polymer monomers | Specific functional groups introduced via palladium-catalyzed coupling, radical reactions, or polymerization processes |
| Organic Synthesis | General synthetic building block for introducing the 2-fluoro-5-benzyl structural motif | Functional group transformations—including alkylation, amination, and cyanation—performed at the benzyl bromide site |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or GC-MS | Quantitative determination using gas chromatography with flame ionization detection or mass spectrometric detection, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | GC-FID or HPLC-UV | Separation and quantification of organic impurities (e.g., 2-fluoro-5-bromobenzyl alcohol, dibromide byproduct) via chromatographic resolution and UV or FID response. |
| Residual Solvents (e.g., DCM, toluene) | GC-FID | Headspace or direct-injection GC-FID analysis to quantify volatile solvents based on calibrated external/internal standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Acidic Impurities (e.g., HBr) | Acid-Base Titration (Non-aqueous) | Titration with standardized tetrabutylammonium hydroxide in glacial acetic acid medium using potentiometric or visual endpoint detection. |
| Heavy Metals (Pb, Cd, Ni, etc.) | ICP-MS or ICP-OES | Digestion followed by inductively coupled plasma mass spectrometry or optical emission spectroscopy for trace metal quantification at sub-ppb levels. |
| Halogens (Total Bromine/Fluorine) | Combustion Ion Chromatography (CIC) | High-temperature combustion to convert halogens to halide ions, followed by suppressed ion chromatography with conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis using controlled heating rate to determine solid-to-liquid phase transition temperature range per pharmacopeial standards. |
| Appearance & Color | Visual Inspection / Hazen/APHA Color Scale | Subjective assessment against water-white reference; color quantified by matching to platinum-cobalt standard solutions. |
| Density / Specific Gravity | Digital Density Meter (Oscillating U-tube) | Measurement of sample density at 20 °C via resonant frequency shift of a vibrating U-shaped glass tube filled with the liquid. |
| Refractive Index | Digital Refractometer | Determination of refractive index at 20 °C using Snell’s law via critical angle measurement of monochromatic light (e.g., sodium D-line). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=99.0% (GC-MS) |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72–76°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.